Temporary Mechanical Circulatory Support (tMCS)

Cardiogenic shock management is not currently standardised due to the absence of high level of evidence coming from randomised control studies. Nevertheless, mechanical circulatory support is increasingly used in the advanced SCAI stages to maintain/improve the haemodynamic to bridge the patient to different potential exit strategies.
There is no data regarding the different tMCS allocation and management except for high level academic centres contributing to network data collection or registries.
The aim of the current survey is to investigate, at investigator-driven level, management pathways of patient undertaking tMCS since the validation process to the weaning.
This is intended to frame similarities and differences across the different physicians who will respond to the survey. It may work as first-step to implement future research aiming at gathering patient's data from centres which will be potentially willing to participate to inception studies and, ultimately, filling the gaps
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1.Please confirm that you have read the above and agree to participate in this survey
Organisation
2.In which country/state do you work?
3.Kind of hospital (tick all that apply):
4.Please indicate
5.Which is your role in the unit?
6.How many Cardiac ICU beds are there in your unit?
7.How many MCS have you managed over the last 12 months?
<5
5-25
>25
IABP
ECMO
Micro axial flow pumps
Others
8.Which programmes does your institution/unit offer? (tick all that apply)
Yes
No
Primary coronary intervention hub (24/7)
Cardiogenic shock hub
Cardiac arrest hub
Shock team 24/7 on site
Shock team 24/7 on call
eCPR centre
Transplant centre
LVAD centre
ECMO retrieval programme
ECMO cannulation on field programme
Donation After Circulatory Death programme
Donation After brain Death programme
9.Does your hospital/unit perform periodic training refreshers/educational programmes on tMCS management?
10.Which devices/procedures are available at your institution? (Tick all that apply)
11.Where are the cardiogenic shock patients on temporary mechanical circulatory support transferred after the implantation at your hospital? (tick all that apply)
General/Mixed ICU
Cardiac ICU/coronary care unit
Cardiac Surgery ICU
V-A ECMO
mAFP (micro axial flow pump)
Clinical evaluation and ICU monitoring
12.How often do you use a PA Catheter to inform on the need of tMCS?
13.How often do you monitor patients already on tMCS? (tick all that apply)
Never
Rarely (1%-30%)
Occasionally (31%-50%)
Regularly (51-90%)
Always (>90%)
PA catheter
Echocardiography
Thermodilution/CO monitoring devices
Basic clinical/hemodynamic monitoring (blood pressure, heart rate, urine output)
Biomarkers (lactate, pCO2-gap, SVO2,……)
Individual tMCS-devices
Intra-aortic balloon pump
14.Do you use IABP at your institution?
15.Where is it routinely implanted?
16.Which are the main indications for IABP placement? (tick all that apply)
17.In patients supported with IABP alone (i.e., not for ACS treatment), which of the following medications do you administer to prevent thrombotic complications, assuming no contraindications?
Yes
No
Antiplatelets
Anticoagulation
Nothing
V-A ECMO
18.Do you use V-A ECMO at your institution?
19.Do you routinely insert distal or antegrade limb perfusion catheter at the time of ECMO cannulation?
20.Where is the V-A ECMO mostly implanted (except for eCPR)?
Never
Rarely (1%-30%)
Occasionally (31%-50%)
Regularly (51-90%)
Always (>90%)
Bedside
Cathlab
Theatre/operating room
Hybrid room
21.During the ECMO treatment, do you monitor: any of the following?
Never
Rarely (1%-30%)
Occasionally (31%-50%)
Regularly (51-90%)
Always (>90%)
Cannula position
Cardiac function with echo
Lung ultrasound
Chest X ray
Abdominal ultrasound
Pre/post oxygenator pressures
Pre/post oxygenator gas exchanges
Oxygenator shunt fraction
D-dimer
Plasma free HB
Aptoglobin – haptoglobin
aPTT
Anti Xa
Activated clotted time
22.Do you have a sweep flow and FiO2 titration protocol?
23.Which is the tidal volume strategy you usually apply in V-A ECMO patient?
24.How do you manage Harlequin syndrome (North-South syndrome)? Tick all that apply
25.Once on tMCS, do you try to completely wash out from
Yes
No
Inotropes
Vasopressors
Axial Flow device
26.Do you use mAFP (micro axial flow pump) at your institution?
27.Which is/are the most common reason(s) to escalate from Impella CP to Impella 5.5 (except for transplant)?
28.Do you monitor any of the following? (multiple ticks):
Never
Rarely (1%-30%)
Occasionally (31%-50%)
Regularly (51-90%)
Always (>90%)
Cannula position with ultrasound
Cardiac function with echo
Lung ultrasound
Chest X ray
Leg perfusion (with Doppler/ultrasound or NIRS)
D-dimer
Plasma free HB
Aptoglobin
aPTT
Anti Xa
Activated clotted time
29.Do you systematically use in the purge solution for any case ?
30.How do you manage the Impella and vasopressor/inotropes once Impella has started?
Never
Rarely (1%-30%)
Occasionally (31%-50%)
Regularly (51-90%)
Always (>90%)
Leave at P9 with same drug setting for 2-4 hours
Leave at P9 reducing vasopressors first and then inotropes
Leave at P9 reducing inotropes first and then vasopressors
Immediately down-titrate to the minimum P level sustainable
31.Do you have a P level titration protocol?
32.If yes, how often is it based on any of the following?
Never
Rarely (1%-30%)
Occasionally (31%-50%)
Regularly (51-90%)
Always (>90%)
Basic hemodynamic data (HR, BP)
Echocardiography
Advanced hemodynamic data (PA cath)
Organ perfusion assessment (lactate, biochemistry)
SMART assist
Unloading
33.How often do you place a device for mechanical unloading at the time of ECMO cannulation?
34.Which kind of unloading strategies do you apply at your institution (tik all that apply)?
35.How do you assess the efficacy of unloading?
Not at all efficacious
Not really efficacious
Average
Efficacious
Very efficacious
Echocardiography (TTE/TOE):
Blood pressure trace
Pulmonary capillary wedge pressure
Lactate clearance
Onset/refractory arrhythmias
Weaning
36.Do you have a standardised weaning protocol?
Yes
No
ECMO
IABP
LV mAFP (micro axial flow pump)
RV mAFP (micro axial flow pump)
37.For femoral V-A ECMO support, what type of decannulation approach do you prefer?
38.Which weaning liberation protocol do you adopt in V-A ECMO supported patients's (tick all that apply)?
39.Which weaning protocol do you adopt in axial flow device supported patients?
40.Echocardiography (TTE/TOE)
Which are the paramenters that you consider for the readiness to liberation?
Never
Rarely (1%- 30%)
Occasionally (31-50%)
Regularly (51%-90%)
Always (>90%)
LVEF
MAPSE
TAPSE
Strain speckle/tracking
3D
LV VTI
Valvular assessment
RV/LV interaction
Total isovolumic time (tIVT)
TAPSE/PASP
E/e’
41.Invasive measurement
Which are the paramenter that you consider for the readiness to liberation?
Never
Rarely (1%- 30%)
Occasionally (31-50%)
Regularly (51%-90%)
Always (>90%)
Co thermodilution
CO Fick
PCWP
PAPi
RAP
Pulse pressure
CPO
Lactate
PCO2 gap
SvO2/ScvO2
Stable VIS
Capillary refill time
42.Do you regularly (> 51%) start inotropes/vasopressors prior to initiating the liberation process if a patient is not already ongoing?
43.Do you use vascular pre-closure devices for arterial cannula/device removal?
Never
Rarely (1%- 30%)
Occasionally (31-50%)
Regularly (51%-90%)
Always (>90%)
Only in case of on going or high risk vascular complication
ECMO
IABP
mAFP (micro axial flow pump)
44.Do you perform a vascular evaluation of limbs after tMCS removal?
V-A ECMO
Impella
Always with ultrasound
Always with angiography
With ultrasound only in case of known vascular complication
With angiography in case of known vascular complication
Never
Outcome and follow up
45.Do you consider starting the guidelines directed polypill therapy (if cardiac and organ function allow)?
During tMCS
After weaning
After ICU discharge
Before Hospital discharge
Never
Beta-blockers
ACE
ARB
ARNi
MRAs
SGLT-2
Ivabradine
46.Would you be willing to participate at centre or network level to a prospective data collection for a specific time frame (inception study)?
If yes, please send an email to escacute@escardio.org and indicate your contact details and your role in the centre where you work
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